Initiating and Titrating Antidepressants

Published on July 6, 2022
By: Dr. Ludwing Salamanca

In the US, most antidepressant prescriptions are written by non-psychiatric providers. Therefore it is important that PCPs understand practices for prescribing. The indications for these medications include unipolar depression, anxiety disorders, post-traumatic stress disorder, obsessive compulsive disorder, and eating disorders.

The selection of antidepressants is usually based on:

  • Presenting symptom profile
  • Side effects, potential drug interactions, and comorbidities
  • Response to previous trials
  • Patient preference
  • Cost

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