The need for further labs to work up his adrenal insufficiency depends on the suspected etiology of his AI. If he had suspected primary failure (again, Conn’s disease), then we’d generally check anti-adrenal/anti-21 hydroxylase antibodies, since they’re the most common etiology. If they were negative, then we would launch into the big ID/infiltrative workup that goes along with HIV: histo, CMV, TB, adrenal hemorrhage, lymphoma, mycobacteria, and Kaposi’s (and sometimes mets, although that’s rare). This would involve the usual serologic testing +/- cultures for all the above in addition to a CT of his adrenals. However, if he was thought to have secondary adrenal insufficiency because of chronic steroid exposure, pituitary injury, narcotics, etc, then we would test the rest of his pituitary function with a TSH, Free T4, IGF-1, and prolactin. We would wait until he was better to check his testosterone and gonadotropins, since acute illness decreases these even in healthy people. While you’re waiting on endocrine to see him, I’d also follow his electrolytes, since people with primary AI are at risk of hyperkalemia. Given the huge dose of steroid he’s on, he’s also at risk of hyperglycemia, so I’d watch out for that. I hope this is helpful. He sounds sick. Please message me back as more issues come up with his care.